British Leprosy Relief Association
Odontogenic infections and leprosy reactions: A case–control study
D. C. B. Cortela et al.
Odontogenic infections and leprosy reactions
Boamorte CortelaDenise Costaa
Sales NogueiraMaria Renatab
De Souza JuniorAlcione Lescanoa
aSchool of Health Sciences, State University of Mato Grosso, Cáceres – MT, Brazil
bResearch Department, Instituto Lauro de Souza Lima, Bauru – SP, Brazil
Correspondence to: Denise Costa Boamorte Cortela, Rua da Maravilha, 1590 – Bairro Cavalhada, Cáceres-MT – CEP 78.200-000 (e-mail: firstname.lastname@example.org)
To analyze the association between reactional episodes in leprosy and clinical and radiographic parameters relating to dental and gingival-periodontal structures of oral health.
Observational case-control study unpaired with multibacillary leprosy patients evaluated between August 2012 and January 2014 from three endemic Brazilian municipalities; patients with first leprosy reaction (cases) were compared to patients without leprosy reaction (controls). The independent variables were grouped into: sociodemographic, disease clinical characteristics, behavior and lifestyle and dental and gingival-periodontal conditions. Two dentists were assigned to the fieldwork and the Kappa statistic was calculated. Logistic regression with 95% confidence interval was carried out.
The study included 57 individuals, including 23 reaction cases (40.4%) and 34 controls (59.6%). Chronic periodontal disease (CPD) (ORaj = 4.3; p = 0.033); the necessity for tooth extraction (ORaj = 23.4; p = 0.006), the presence of bone loss (ORaj = 6.5; p = 0.030), the presence of periodontal pockets (ORaj = 3.4; p = 0.045) and a visit to the dentist (ORaj =0.3; p = 0.014) are associated with reactional episodes in leprosy.
The dental and gingival-periodontal parameters shown to be associated with reactional episodes in leprosy were the presence of teeth that need to be extracted, CPD, and the presence of a periodontal pocket. Alveolar bone reabsorption was a radiographic parameter associated with reactional episodes in leprosy.
LeprosyPeriodontal medicineDental infectionsOral health