LEPROSY
Leprosy Review
0305-7518
British Leprosy Relief Association
Colchester, UK
25-8262
0305-7518/05/064053+05
10.47276/lr.76.3.258
Case Report
Reversal reaction and Mitsuda conversion in polar lepromatous leprosy: a case report
B. R. Kar and C. K. Job
Reversal reaction and Mitsuda conversion in polar lepromatous leprosy: a case report
JobC. K.
ba
Department of Dermatology and
b
Department of Pathology, SLR & TC, Karigiri, Vellore 632106, India
Correspondence to: B. R. Kar (e-mail: karbikash@hotmail.com)
01092005
76
3
258
262
01062005
© Lepra
2005
A 22-year-old male polar lepromatous leprosy patient who became Mitsuda positive after 36 months of multidrug therapy (MDT) is reported. Lepromatous leprosy (LL) is a state of specific immunosuppression and is invariably irreversible. The finding of Mitsuda positivity in histopathologically proven polar lepromatous leprosy is extremely uncommon, and conversion of lepromin status following MDT has not so far been reported. This case reports confirms the observations made by Waters et al. 1 regarding lepromin conversion in lepromatous patients.